Sai Hanuman Sagar Boddu

Sai Hanuman Sagar Boddu

Associate Professor
Ext: 6950

Dr. Sai HS. Boddu is an Associate Professor of Pharmaceutics in the College of Pharmacy and Health Sciences, Ajman University (AU). Dr. Boddu received his Ph.D. in Pharmaceutical Sciences from the University of Missouri-Kansas City. Prior to joining AU, he worked for the University of Toledo for 7.5 years. Dr. Boddu holds 2 patents and published more than 90 research and review articles in various peer-reviewed journals. Dr. Boddu is a co-Editor of the book titled "Excipient Applications in Formulation Design and Drug Delivery". Dr. Boddu’s current research interests are developing novel drug delivery systems for treating various diseases.

Education
  • Ph.D. in Pharmaceutical Sciences, University of Missouri-Kansas City, USA, 2010
  • Masters in Pharmaceutics, NDMVP SAMAJ’S College Of Pharmacy, Nashik, Maharashtra, India
  • Bachelors in Pharmaceutics, Bapatla College of Pharmacy, Bapatla, Andhra Pradesh, India
Experience
  • Associate Professor, Department of Pharmaceutical Sciences, Ajman University, Ajman, UAE, August, 2018 - current
  • Associate Professor, Department of Pharmacy Practice, University of Toledo, USA, August, 2016 - August, 2018
  • Assistant Professor, Department of Pharmacy Practice, University of Toledo, USA, February, 2011-August, 2016
  • Research Associate Wockhardt Research Center Chikalthana, Aurangabad, Maharashtra, India, August, 2005-August, 2006
Teaching Area
  • Pharmaceutics, Dosage forms, Pharmacokinetics
  • Biopharmaceutics
  • Clinical Pharmacokinetics
Research
  • Drug delivery, Novel drug delivery systems
Publications
  • Bahl, D., Daftardar, S., Bachu, R. D., Boddu, S. H., Altorok, N., & Kahaleh, B. (2019). Evaluation of Topical Econazole Nitrate Formulations with Potential for Treating Raynaud’s Phenomenon. Pharmaceutical development and technology, 24 (6), 689-699
  • Bhattarai, R., Bachu, R., Boddu, S., & Bhaduri, S. (2019). Biomedical applications of electrospun nanofibers: Drug and nanoparticle delivery. Pharmaceutics, 11(1), 5.
  • Neupane, R., Gaudana, R., Boddu, SHS. Imaging Techniques in the Diagnosis and Management of Ocular Tumors: Prospects and Challenges. The AAPS journal, 2018, 20(6), 97.
  • Adhikari S, Daftardar S, Fratev F, Rivera M, Sirimulla S, Alexander K, Boddu SHS. Elucidation of the Orientation of Selected Drugs with 2-Hydroxylpropyl-β-Cyclodextrin Using 2D-NMR Spectroscopy and Molecular Modelling. International journal of pharmaceutics. 2018 May 7.
  • Kalhapure RS, Bolla P, Dominguez DC, Dahal A, Boddu SHS, Renukuntla J, Furosemide- silver complex nanosuspension: preparation and evaluation of antibacterial activity, IET Nanobiotechnology. 2018 Apr 6.
  • Cruz KCE, Churchwell MD, Mauro VF, Boddu SHS. Physical compatibility of levetiracetam injection with heparin, dobutamine, and dopamine. Am J Health Syst Pharm., 2018, 75(8):510-512.
  • Bachu RD, Chowdhury P, Al-Saedi ZH, Karla PK. and Boddu SHS. Ocular Drug Delivery Barriers—Role of Nanocarriers in the Treatment of Anterior Segment Ocular Diseases. Pharmaceutics, 2018, 10(1), p.28.
  • Bachu RD, Stepanski M, Alzhrani R, Jung R, Boddu SHS. Development and Evaluation of a Novel Microemulsion of Dexamethasone and Tobramycin for Topical Ocular Administration, Journal of Ocular Pharmacology and Therapeutics. 2018, 34(4), 312-324
  • Wei Y, Yang JW, Boddu SHS, Jung R, Churchwell MD. Compatibility, Stability, and Efficacy of Vancomycin Combined With Gentamicin or Ethanol in Sodium Citrate as a Catheter Lock Solution. Hosp Pharm. 2017 Nov;52(10):685-690.
  • Alzhrani RM, Alhadidi Q, Bachu RD, Shah Z, Dey S, Boddu SHS, (2017) Tanshinone IIA Inhibits VEGF Secretion and HIF-1α Expression in Cultured Human Retinal Pigment Epithelial Cells Under Hypoxia, Curr Eye Res. 2017 Dec;42(12):1667-1673.
  • Bhattarai RS, Das A, Alzhrani RM, Kang D, Bhaduri SB, Boddu SHS, Comparison of Electrospun and Solvent Cast Polylactic acid (PLA)/Poly(vinyl alcohol) (PVA) Inserts as Potential Ocular Drug Delivery Vehicles, Materials Science and Engineering: C 77 (2017): 895-903
  • Alsaab H, Alzhrani RM, Kesharwani P, Sau S, Boddu SHS, Iyer AK, (2017). Folate Decorated Nanomicelles Loaded with a Potent Curcumin Analogue for Targeting Retinoblastoma. Pharmaceutics, 2017, 9(2), 15.
  • Frank MI, Boddu SHS, Mauro VF, Churchwell MD. Physical compatibility of valproate sodium injection with dobutamine and dopamine. American Journal of Health-System Pharmacy. 2017, 74(5):280-281.
  • Alsaab H, Bonam SP, Bahl D, Chowdhury P, Alexander K, Boddu SHS. Organogels in Drug Delivery: A special emphasis on Pluronic Lecithin Organogels. J Pharm Pharm Sci. 2016 Apr-Jun;19(2):252-73.
  • Al-Saedi Z, Zimmerman A, Bachu RD, Dey S, Shah Disease: Present Challenges in the Management and design. Curr Pharm Des. 2016;22(28):4470-90
  • Al-Saedi ZH, Alzhrani RM, Boddu SHS. Formulation and In Vitro Evaluation of Cyclosporine-A Inserts Prepared Using Hydroxypropyl Methylcellulose for Treating Dry Eye Disease. Journal of Ocular Pharmacology and Therapeutics. J Ocul Pharmacol Ther. 2016 Sep;32(7):451-62.
  • Peeters Michael, Boddu SHS, Assessing Development in Critical Thinking: One Institution’s Experience, Currents in Pharmacy Teaching and Learning, 8(3), 271-278.
  • Alsaab H, Alzhrani RM, Boddu SHS. Evaluation of the Percutaneous Absorption of Chlorpromazine from PLO Gels across Porcine Ear and Human Abdominal Skin, Drug Dev Ind Pharm. 2016 Aug;42(8):1258-66
  • Patel S, Garapati C, Chowdhury P, Gupta H, Nesamony J, Nauli S, Boddu SHS. Development and Evaluation of Dexamethasone Nanomicelles with Potential for Treating Posterior Uveitis After Topical Application.J Ocul Pharmacol Ther. 2015, 31(4): 215-227.
  • Rao PS, Goodwani S, Bell RL, Wei Y, Boddu SHS, Sari Y. Effects of ampicillin, cefazolin and cefoperazone treatments on GLT1 expressions in the mesocorticolimbic system and ethanol intake in alcohol-preferring rats. Neuroscience. 2015, 295, 164-174.
  • Kalhapure RS, Bolla PK, Boddu SHS, Renukuntla J. Evaluation of Oleic Acid and Polyethylene Glycol Monomethyl Ether Conjugate (PEGylated Oleic Acid) as a Solubility Enhancer of Furosemide. Processes. 2019 Aug;7(8):520.
  • Amawi H, Hussein N, Boddu SHS, Karthikeyan C, Williams FE, Ashby Jr CR, Dayanidhi R, Trivedi P, Tiwari A. The Novel Thienopyrimidine Derivative, RP-010, Produces Its Efficacy in Prostate Cancer Cells by Inducing the Fragmentation of β-catenin, Cancers, 2019: 11 (5), 711
  • Dahal A, Neupane R, Boddu SHS, Renukuntla J, Khupse R, Dudley R. Percutaneous Absorption of Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol from ABH Gel. International journal of pharmaceutical compounding. 2020;24(2):168.
  • Godage NH, Cudjoe E, Neupane R, Boddu SHS, Bolla PK, Renukuntla J, Gionfriddo E. Biocompatible SPME fibers for direct monitoring of nicotine and its metabolites at ultra trace concentration in rabbit plasma following the application of smoke cessation formulations. Journal of Chromatography A. 2020 Jun 11:461333
  • Amawi H, Hussein N, Boddu SHS, Karthikeyan C, Williams FE, Ashby Jr CR, Dayanidhi R, Trivedi P, Tiwari A. The Novel Thienopyrimidine Derivative, RP-010, Produces Its Efficacy in Prostate Cancer Cells by Inducing the Fragmentation of β- catenin, Cancers, 2019: 11.5, 711.
  • Kalhapure RS, Bolla PK, Boddu SHS, Renukuntla J, Evaluation of Oleic Acid and Polyethylene Glycol Monomethyl Ether Conjugate (PEGylated Oleic Acid) as a Solubility Enhancer of Furosemide, Processes, 2019: 7 (8), 520
  • Daftardar S, Bahl D, Boddu SHS, Nezam A, Bashar K. Ultrasound-Mediated Topical Delivery of Econazole Nitrate with Potential for Treating Raynaud's Phenomenon. International Journal of Pharmaceutics. 2020 Mar 14:11922.
  • Natesan S, Boddu SHS, Krishnaswami V, Shahwan M. The Role of Nano- ophthalmology in Treating Dry Eye Disease, Pharmaceutical Nanotechnology 8 (4), 258-289.
  • Boddu SHS, Tukaramrao DB, Al-Tabakha, MM, Ashames A, Neupane R, Babu RJ, Renukuntla J. and Tiwari AK, Evaluation of Cytotoxicity and Taste-Masking Effect of Selected Flavors on Dental Lidocaine HCl Injection, 13.11 (2020): 353.
  • Boddu SHS, Kumari Sneha, Design and In Vitro Evaluation of Intranasal Diazepam for Treating Acute Repetitive Seizures: a Technical Note, Journal of Pharmaceutical Innovation, publication date: 19/11/2020
  • Boddu SHS, Kumari Sneha, A Short Review on the Intranasal Delivery of Diazepam for Treating Acute Repetitive Seizures, Pharmaceutics, 12 (12), 1167.
  • Amawi H, Aljabali A, Boddu SHS et al., The use of zebrafish model in prostate cancer therapeutic development and discovery. Cancer Chemother Pharmacol. 2021, 1-15
  • Rodriguez VA, Bolla PK, Kalhapure RS, Boddu SHS, Neupane R, Franco J, Renukuntla J. Preparation and Characterization of Furosemide-Silver Complex Loaded Chitosan Nanoparticles. Processes. 2019 Apr;7(4):206.
  • Kalhapure RS, Bolla PK, Boddu SHS, Renukuntla J, Evaluation of Oleic Acid and Polyethylene Glycol Monomethyl Ether Conjugate (PEGylated Oleic Acid) as a Solubility Enhancer of Furosemide, Processes, 2019: 7 (8), 520
  • Namdeo AG, Boddu SHS, Amawi H, Ashby Jr CR, Tukaramrao DB, Trivedi P, Babu RJ, Tiwari AK. Flavonoids as Multi-Target Compounds: A Special Emphasis on their Potential as Chemo-adjuvants in Cancer Therapy. Current Pharmaceutical Design. 2020 Apr 1;26(15):1712-28.
  • Neupane R, Boddu SHS, Renukuntla J, Babu RJ, Tiwari AK. Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities. Pharmaceutics. 2020 Feb;12(2):152.
  • Dobson SR, Mauro VF, Boddu SHS, Churchwell MD. The Physical Compatibility of Clinically Used Concentrations of Diltiazem Hydrochloride with Heparin Sodium. Journal of Pharmacy Technology. 2020 May 23:8755122520924767.
  • Annaji M, Poudel I, Boddu SH, Arnold RD, Tiwari AK, Babu RJ. Resveratrol‐loaded nanomedicines for cancer applications. Cancer Reports. 2021 Mar 2:e1353.
  • Peeters M, Cor MK, Boddu S, Nesamony J. Validation Evidence from using Generalizability Theory in a Basic-Science Course: Reliability of Course-Grades From Multiple Examinations. INNOVATIONS in pharmacy. 2021 Feb 26;12(1):16
Conference Presentation
  • Peeters MJ, Cor MK, Boddu SHS, Nesamony J, Applying Generalizability Theory to Provide Validity Evidence for a Pharmaceutics Course Grade: Combining Exam Reliability Coefficients. 119th Annual Meeting of the American Association of Colleges of Pharmacy, Boston, Massachusetts, July 21-25, 2018
  • Sai HS. Boddu, ​Ultrasound-mediated Transdermal Delivery of Econazole Nitrate For Treating Raynaud's Phenomenon​ at the 2019 Controlled Release Society Annual Meeting & Exposition in Valencia, Spain, July 21-24, 2019
  • Boddu SHS et al., “Ultrasound-mediated Transdermal Delivery of Econazole Nitrate For Treating Raynaud's Phenomenon” at the 2019 Controlled Release Society Annual Meeting & Exposition in Valencia, Spain, July 21-24, 2019
  • Bolla PK, Boddu SHS et al., Development and In Vitro Characterization of Folate Conjugated PLGA Nanoparticles of Lutein, AAPS 2020 New Orleans in USA, Oct 26- 28, 2020
Memberships, Awards and Honors
  • University of Missouri-Kansas City, Vice Chancellor for Student Affairs and Enrollment Management Honor Recipient, Fall-2010
  • University of Missouri-Kansas City -Chancellor's Doctoral Fellowship, Fall 2008-Fall 2010
  • University of Missouri-Kansas City -Chancellor Non-Resident award, Fall, 2006-Fall,2010
  • University of Missouri-Kansas City, Best poster award for Research Day, 2010
  • AAPS-UMKC Best seminar speaker award, 2008
  • University of Missouri-Kansas City, 24th Annual Achievers of Excellence award, 2006
  • Principal Investigator, Design and Characterization of an Improved Lidocaine HCl Formulation for Dental Procedures” Research contract grant, Funded by: Neocaine, LLC, USA, AED 440760.00 (Funded), 06/2020 -06/2022
  • Principal Investigator, Taste Masking of Injectable Lidocaine HCl Formulation for Dental Procedures”, Interdisciplinary Research Grant, Funded by: Ajman University, Date: October 1st, 2019 (Funded), 10/2109-09/2020, Amount: AED 49,760
  • Principal Investigator, Development and characterization of nicotine loaded solid lipid nanoparticle hydrogels, Sponsor: Paso del Norte Health Foundation, Prime Grantee: The University of Texas at El Paso, 1/1/2018 to 2/28/2019, Amount: $11000.
  • Principal Investigator, Development and validation of an SPME-GC-MS method for determination of fluasterone in rabbit plasma, University of Texas at El Paso, Date: 7/1/18-8/31/18, Amount: $8000.
  • Principal Investigator, Development and Characterization of Tanshinone IIA Microparticles for Sustained Therapy in Age Related Macular Degeneration, University of Toledo, Date: 06/12/2017, Amount: $5000
  • Principal Investigator, In vitro release of model drugs from silicone–based elastomers and elastomer gels, Wacker Chemical Corporation, Date: 12/12/2016, Amount: $30,500
  • Principal Investigator, Solubility and Stability of Diazepam in Selected Solvent, Total care pharmacy, Date: 12/12/2016, Amount: $6,500.
  • Principal Investigator, “Electrospun Ophthalmic Inserts for Extended Delivery of Bimatoprost in Glaucoma Therapy”, deArce-Koch Memorial Endowment Fund in Support of Medical Research and Development, Date: 05/01/2015 - 05/01/2016, Amount: $10,000.
  • Principal Investigator, “To study the dermal absorption of cosmetic products across fresh human tissue samples”, L’Oréal Collaborative Project, Date of submission: 06/27/2014. Amount: $12,483
  • Principal Investigator, “Preparation and Evaluation of a Pluronic Lecithin Organogel Containing Ricinoleic acid for the Transdermal Delivery of Ketoprofen”, International Academy of Compounding Pharmacists”, Date: 02/01/2013 - 02/01/2014, Amount: $ 9,980.
  • Co-Investigator, “Waters Academic Grant Program”, Duration: 10/30/2012 - 10/29/2014
  • Co- Investigator, “Preclinical Evaluation of Photodynamic Therapy for the Treatment of Chronic Sinusitis,” The Translational Research Stimulation Award program, Principal Investigator: Reginald Baugh, MD, Professor of Surgery, Date:05/01/2012 – 05/01/2013. $25,000.00
  • Collaborating Investigator, “Novel Trans-Scleral Delivery Strategy using Bimatoprost Nanoparticles given Subconjunctivally for the Treatment of Glaucoma”, St. Luke’s Hospital Foundation, $24,600.00, 11/01/2009 – 10/31/2010