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Yehia Saleh Ahmed Mohamed
- Associate Professor
- Ext: 5337
Dr. Yehia is an associate professor of immunology. He gained his undergraduate degree from Al-Azhar University in Cairo, Egypt. The Department of Infection, Immunity, and Inflammation at Leicester University Medical School, UK (ranked 272nd worldwide according to the QS report 2024), awarded Dr. Yehia his PhD. His teaching journey had many destinations in different regions, including the Middle East, Europe, and North America, during which he was focusing on subject-related curriculum development, course coordination, student counseling, and community service. Dr. Yehia is interested in many areas of research, such as using immunotherapy to treat cancerous tumors, especially hematologic cancers, making vaccines to fight long-lasting viruses, and studying how new therapeutic drugs affect the immune system.
Education
- Postdoctoral fellowship; molecular HIV-1 vaccine development, Jenner Institute, Oxford University, UK. 2018
- PhD; Infection, Immunity, and Inflammation, at Leicester University, UK, 2012
- B. Pharm; Al-Azhar University, Cairo, Egypt.
Postdoctoral fellowship; molecular HIV-1 vaccine development, Jenner Institute, Oxford University, UK. 2018
PhD; Infection, Immunity, and Inflammation, at Leicester University, UK, 2012
B. Pharm; Al-Azhar University, Cairo, Egypt.
Experience
- College of Medicine, Ajman University, Associate Professor, Sep 2020 - present
- Western University, London-Ontario, Visiting Research Scholar, 2019- 2020
- Jenner Institute, Oxford University, UK, Immunology Research Scientist, 2017- 2019
- Department of Medical Microbiology, College of Medicine, IAU, Saudi Arabia, Assistant Professor, 2012 – 2017
- PhD Candidate, Research Assistant, Department of Infection, Immunity, and Inflammation, Leicester University, UK. 2007- 2012
College of Medicine, Ajman University, Associate Professor, Sep 2020 - present
Western University, London-Ontario, Visiting Research Scholar, 2019- 2020
Jenner Institute, Oxford University, UK, Immunology Research Scientist, 2017- 2019
Department of Medical Microbiology, College of Medicine, IAU, Saudi Arabia, Assistant Professor, 2012 – 2017
PhD Candidate, Research Assistant, Department of Infection, Immunity, and Inflammation, Leicester University, UK. 2007- 2012
Teaching Area
- Basic Medical Immunology
- Clinical and Diagnostic Immunology
- Microbiology and Infectious Diseases
Basic Medical Immunology
Clinical and Diagnostic Immunology
Microbiology and Infectious Diseases
Research
- Cellular and adoptive immunotherapy of malignant tumors
- Immunologic evaluation of molecular vaccine candidates for chronic viral infections
- The immunomodulatory profiling of newly approved therapeutic agents
- Clinical trials and survey studies related to communicable and non-communicable chronic diseases.
Cellular and adoptive immunotherapy of malignant tumors
Immunologic evaluation of molecular vaccine candidates for chronic viral infections
The immunomodulatory profiling of newly approved therapeutic agents
Clinical trials and survey studies related to communicable and non-communicable chronic diseases.
Publications
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JournalDebadatta Panigrahi, Erum Khan, Yehia Mohamed and Ashok Rattan. , Factors Affecting Patients Test Results". Acta Scientific Microbiology 5.10 (2022): 59-67., Act Scientific Microbiology, Vol: 5, pp.59 - 67, Sep 2022
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Mohamed A. Baraka, Amany Alboghdadly, Samar Alshawwa, Asim Ahmed Elnour, Hassan Alsultan, Taha Al, Hussain Alaithan, Md. Ashraful Islam, Kareem Ahmed El-Fass, Yehia Mohamed, Abdulsalam A. Alasseri and Khairi Mustafa Fahelelbum. Perspectives of Healthcare Professionals Regarding Factors Associated with Antimicrobial Resistance (AMR) and Their Consequences: A Cross Sectional Study in Eastern Province of Saudi Arabia. Antibiotics 2021, 10, 878. https://doi.org/10.3390/antibiotics10070878
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Yehia S. Mohamed, Nicola J. Borthwick, Nathifa Moyo, Hayato Murakoshi, Tomohiro Akahoshi, Zara Hannoun, Alison Crook, Patricia E. Fast, Gaudensia Mutua, Walter Jaoko, Sandra Silva-Arrieta, Anuska Llano, Christian Brander, Masafumi Takiguchi, and Tomáš Hanke. Specificity of CD8 T-Cell Responses following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya. Vaccines 2020, 8(2), 260 https://www.mdpi.com/2076-393X/8/2/260 2
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Yehia S. Mohamed, Borthwick N, Hanoon Z. Mapping of HIV-1 CD8 T-cell epitopes in East African recipients of conserved-region T-cell vaccines. BSI congress. Dec 2019. https://www.eventsforce.net/bsi/frontend/reg/absViewDocumentFE.csp?documentID=265
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Wafaa S.S. Khalaf, Mamta Garg, Yehia S. Mohamed, Cordula Stover, Michael J Browning. In vitro generation of cytotoxic T cells with the potential for adoptive tumour immunotherapy of Multiple Myeloma. Frontiers Immunology. Aug. 2019; (10): 1792. https://doi.org/10.3389/fimmu.2019.01792
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Eman Y. Abu-Rish, Lina A. Dahabiyeh, Yasser Bustanjia, Yehia S. Mohamed, Michael J. Browning. Effect of lamotrigine on in vivo and in vitro cytokine secretion in murine models of inflammation. Neuroimmunology. Sep. 2018; (322): 36-45. https://doi.org/10.1016/j.jneuroim.2018.06.008
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Eman Y. Abu-Rish, Shada Y. Elhayek, Yehia S. Mohamed, Islam Hamad and Yasser Bustanji. Evaluation of immunomodulatory effects of lamotrigine in Balb/c mice. Acta Pharm. Sept. 2017; 67(4) https://doi.org/10.1515/acph-2017-0035
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Yehia S. Mohamed, Wafaa Khalaaf and Michael Browning. APC / tumour cell hybrid vaccines in cancer immunotherapy. Immunotherapy - Myths, Reality, Ideas and Future. InTech Open access publishing, April 2017. Edited by Krassimir Metodiev, ISBN 978-953-51-3106-9. https://www.intechopen.com/books/immunotherapy-myths-reality-ideas-future
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Yehia S. Mohamed, Layla A. Bashawri, Chittibabu Vatte, Cyril Cyrus, Eman Y. Abu-rish, Wafaa S. Khalaaf and Michael J. Browning. The in vitro generation of multi-tumor antigen-specific cytotoxic T cell clones: Candidates for leukemia adoptive immunotherapy following allogeneic stem cell transplantation. Molecular Immunology. Sept. 2016; (77):79–88. https://doi.org/10.1016/j.molimm.2016.07.012
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Eman Y. Abu-Rish, Mohammad K. Mohammad, Mohammad M. Hudaib, Sundus Mashalla, Loay Mashallah, Violet Kasabri, Khaled Tawaha, Yehia S. Mohamed, Yasser K. Bustanji. Evaluation of the antiproliferative activity of some traditional anticancer herbal remedies from Jordan. Trop J Pharm Res, March 2016; 15(3): 469. http://dx.doi.org/10.4314/tjpr.v15i3.6
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Yehia S. Mohamed and Michael Browning. Immortalized HMy2/solid tumor hybridomas induce two different tumor antigen-specific T cell clones in vitro. Cancer Immunol Res Jan 2016; (4): B099. https://cancerimmunolres.aacrjournals.org/content/4/1_Supplement/B099
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Al-Amri, Ali M., Vatte, Chittibabub; Cyrus, Cyril, Chathoth, Shahanas, Hashim, Tariq Mohammad, Yehia S. Mohamed, Ali, Rudaynah Ala, Alsaid, Abira, Ali, Amin Al. Novel mutations of the PIK3CA gene in head and neck squamous cell carcinoma. Cancer Biomarkers. Jan. 2016; 16(3) :377-383. http://DOI: 10.3233/CBM-160576
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Yehia S. Mohamed. Tumor-specific cytotoxic T lymphocytes: A candidate for adoptive immunotherapy of hematological malignancies. Clin Pharmacol Biopharm. Nov 2015; 4(4); 124. DOI: 10.4172/2167-065X.C1.014 12
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Yehia S. Mohamed, Debbie Dunnion, Iryna Teobald, Renata Walewska, Sarah Alderson and Michael J. Browning. In vitro evaluation of human hybrid cell lines generated by fusion of Blymphoblastoid cells and ex vivo tumour cells as candidate vaccines for haematological malignancies. Vaccine. Oct 2012; 30(46):6578-87. https://doi.org/10.1016/j.vaccine.2012.08.032 13.
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Yehia S. Mohamed, Debbie Dunnion, Iryna Teobald, Renata Walewska, and Michael J. Browning. Long-lived fusions of human haematological tumour cells and B-lymphoblastoid cells induce tumour antigen-specific cytotoxic T-cell responses in vitro. Immunobiology. July 2012; 217(7):719-29. https://www.sciencedirect.com/science/article/pii/S0171298511002610
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JournalPanigrahi, D., Mohamed, Y.S., Khan, E., Panigrahi, D., Mohamed, Y.S., Khan, E. (2023). Enhancing Lecture Attendance: A Novel Approach Utilizing Clinical Case-Based Learning. Adv Mach Lear Art Inte, 4(2), 41-43., Advances in Machine Learning & Artificial Intelligence(AMLAI), Vol: 4, pp.41 - 43, Oct 2023
Debadatta Panigrahi, Erum Khan, Yehia Mohamed and Ashok Rattan. , Factors Affecting Patients Test Results". Acta Scientific Microbiology 5.10 (2022): 59-67., Act Scientific Microbiology, Vol: 5, pp.59 - 67, Sep 2022
Abstract The clinical diagnostic laboratory plays a very important role in the safe delivery of quality service to the patient. Over 70 percent of all management decisions in clinics and hospitals are based on laboratory results. It is therefore of paramount importance that the laboratory issues out reports that are accurate, reliable, reproducible and available to clinicians in a clinically relevant time frame. The diagnostic cycle can be divided into three phases (which has been further divided into five), with the pre analytical phase being the most error prone. A number of variables effect the results and each variable has to be controlled if we wish to obtain reliable results. Sensitivity and specificity are inherent attributes of a test, but the positive and negative predictive value depends upon the prevalence of the disease in the community. We can increase the value of the test by considering the likelihood ratio and understanding the purpose of the test.
About the journal
Mohamed A. Baraka, Amany Alboghdadly, Samar Alshawwa, Asim Ahmed Elnour, Hassan Alsultan, Taha Al, Hussain Alaithan, Md. Ashraful Islam, Kareem Ahmed El-Fass, Yehia Mohamed, Abdulsalam A. Alasseri and Khairi Mustafa Fahelelbum. Perspectives of Healthcare Professionals Regarding Factors Associated with Antimicrobial Resistance (AMR) and Their Consequences: A Cross Sectional Study in Eastern Province of Saudi Arabia. Antibiotics 2021, 10, 878. https://doi.org/10.3390/antibiotics10070878
Factors reported in the literature associated with inappropriate prescribing of antimicrobials include physicians with less experience, uncertain diagnosis, and patient caregiver influences on physicians’ decisions. Monitoring antimicrobial resistance is critical for identifying emerging resistance patterns, developing, and assessing the effectiveness of mitigation strategies. Improvement in prescribing antimicrobials would minimize the risk of resistance and, consequently, improve patients’ clinical and health outcomes. The purpose of the study is to delineate factors associated with antimicrobial resistance, describe the factors influencing prescriber’s choice during prescribing of antimicrobial, and examine factors related to consequences of inappropriate prescribing of antimicrobial. A cross-sectional study was conducted among healthcare providers (190) in six tertiary hospitals in the Eastern province of Saudi Arabia. The research panel has developed, validated, and piloted survey specific with closed-ended questions. A value of p < 0.05 was considered to be statistically significant. All data analysis was performed using the Statistical Package for Social Sciences (IBM SPSS version 23.0). 72.7% of the respondents have agreed that poor skills and knowledge are key factors that contribute to the inappropriate prescribing of antimicrobials. All of the respondents acknowledged effectiveness, previous experience with the antimicrobial, and reading scientific materials (such as books, articles, and the internet) as being key factors influencing physicians’ choice during antimicrobial prescribing. The current study has identified comprehensive education and training needs for healthcare providers about antimicrobial resistance. Using antimicrobials unnecessarily, insufficient duration of antimicrobial use, and using broad spectrum antimicrobials were reported to be common practices. Furthermore, poor skills and knowledge were a key factor that
About the journal
Yehia S. Mohamed, Nicola J. Borthwick, Nathifa Moyo, Hayato Murakoshi, Tomohiro Akahoshi, Zara Hannoun, Alison Crook, Patricia E. Fast, Gaudensia Mutua, Walter Jaoko, Sandra Silva-Arrieta, Anuska Llano, Christian Brander, Masafumi Takiguchi, and Tomáš Hanke. Specificity of CD8 T-Cell Responses following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya. Vaccines 2020, 8(2), 260 https://www.mdpi.com/2076-393X/8/2/260 2
Yehia S. Mohamed, Borthwick N, Hanoon Z. Mapping of HIV-1 CD8 T-cell epitopes in East African recipients of conserved-region T-cell vaccines. BSI congress. Dec 2019. https://www.eventsforce.net/bsi/frontend/reg/absViewDocumentFE.csp?documentID=265
Wafaa S.S. Khalaf, Mamta Garg, Yehia S. Mohamed, Cordula Stover, Michael J Browning. In vitro generation of cytotoxic T cells with the potential for adoptive tumour immunotherapy of Multiple Myeloma. Frontiers Immunology. Aug. 2019; (10): 1792. https://doi.org/10.3389/fimmu.2019.01792
Eman Y. Abu-Rish, Lina A. Dahabiyeh, Yasser Bustanjia, Yehia S. Mohamed, Michael J. Browning. Effect of lamotrigine on in vivo and in vitro cytokine secretion in murine models of inflammation. Neuroimmunology. Sep. 2018; (322): 36-45. https://doi.org/10.1016/j.jneuroim.2018.06.008
Eman Y. Abu-Rish, Shada Y. Elhayek, Yehia S. Mohamed, Islam Hamad and Yasser Bustanji. Evaluation of immunomodulatory effects of lamotrigine in Balb/c mice. Acta Pharm. Sept. 2017; 67(4) https://doi.org/10.1515/acph-2017-0035
Yehia S. Mohamed, Wafaa Khalaaf and Michael Browning. APC / tumour cell hybrid vaccines in cancer immunotherapy. Immunotherapy - Myths, Reality, Ideas and Future. InTech Open access publishing, April 2017. Edited by Krassimir Metodiev, ISBN 978-953-51-3106-9. https://www.intechopen.com/books/immunotherapy-myths-reality-ideas-future
Yehia S. Mohamed, Layla A. Bashawri, Chittibabu Vatte, Cyril Cyrus, Eman Y. Abu-rish, Wafaa S. Khalaaf and Michael J. Browning. The in vitro generation of multi-tumor antigen-specific cytotoxic T cell clones: Candidates for leukemia adoptive immunotherapy following allogeneic stem cell transplantation. Molecular Immunology. Sept. 2016; (77):79–88. https://doi.org/10.1016/j.molimm.2016.07.012
Eman Y. Abu-Rish, Mohammad K. Mohammad, Mohammad M. Hudaib, Sundus Mashalla, Loay Mashallah, Violet Kasabri, Khaled Tawaha, Yehia S. Mohamed, Yasser K. Bustanji. Evaluation of the antiproliferative activity of some traditional anticancer herbal remedies from Jordan. Trop J Pharm Res, March 2016; 15(3): 469. http://dx.doi.org/10.4314/tjpr.v15i3.6
Yehia S. Mohamed and Michael Browning. Immortalized HMy2/solid tumor hybridomas induce two different tumor antigen-specific T cell clones in vitro. Cancer Immunol Res Jan 2016; (4): B099. https://cancerimmunolres.aacrjournals.org/content/4/1_Supplement/B099
Al-Amri, Ali M., Vatte, Chittibabub; Cyrus, Cyril, Chathoth, Shahanas, Hashim, Tariq Mohammad, Yehia S. Mohamed, Ali, Rudaynah Ala, Alsaid, Abira, Ali, Amin Al. Novel mutations of the PIK3CA gene in head and neck squamous cell carcinoma. Cancer Biomarkers. Jan. 2016; 16(3) :377-383. http://DOI: 10.3233/CBM-160576
Yehia S. Mohamed. Tumor-specific cytotoxic T lymphocytes: A candidate for adoptive immunotherapy of hematological malignancies. Clin Pharmacol Biopharm. Nov 2015; 4(4); 124. DOI: 10.4172/2167-065X.C1.014 12
Yehia S. Mohamed, Debbie Dunnion, Iryna Teobald, Renata Walewska, Sarah Alderson and Michael J. Browning. In vitro evaluation of human hybrid cell lines generated by fusion of Blymphoblastoid cells and ex vivo tumour cells as candidate vaccines for haematological malignancies. Vaccine. Oct 2012; 30(46):6578-87. https://doi.org/10.1016/j.vaccine.2012.08.032 13.
Yehia S. Mohamed, Debbie Dunnion, Iryna Teobald, Renata Walewska, and Michael J. Browning. Long-lived fusions of human haematological tumour cells and B-lymphoblastoid cells induce tumour antigen-specific cytotoxic T-cell responses in vitro. Immunobiology. July 2012; 217(7):719-29. https://www.sciencedirect.com/science/article/pii/S0171298511002610
Panigrahi, D., Mohamed, Y.S., Khan, E., Panigrahi, D., Mohamed, Y.S., Khan, E. (2023). Enhancing Lecture Attendance: A Novel Approach Utilizing Clinical Case-Based Learning. Adv Mach Lear Art Inte, 4(2), 41-43., Advances in Machine Learning & Artificial Intelligence(AMLAI), Vol: 4, pp.41 - 43, Oct 2023
There has been an observable trend indicating a decline in students' attendance at lectures. Several reasons for this have been proposed, and various measures to mitigate this have been suggested in the past. We implemented a novel approach in our instructional strategy to address this. Real-life clinical problems relevant to the topic were integrated into the lectures, and they were deliberately excluded from the pre-lecture handouts. During the lectures, students were motivated to post questions and actively engage in peer-to-peer and peer-tutor discussions. To evaluate the impact of this intervention, student attendance before and after was monitored, calculated and statistically analyzed to get the average attendance. The results revealed a significant increase in the average attendance, demonstrating a statistically meaningful difference (p
About the journal
Conference Presentation
- The 7th International Conference of Faculty of Pharmacy- Al-Azhar University, Cairo, Egypt. 22-23 Oct 2022. Poster title: "Perspectives of Healthcare Professionals Regarding Factors Associated with Antimicrobial Resistance (AMR) and Their Consequences, a cross sectional study in multiple Saudi Hospitals."
- The 4th European Conference on Vaccines and Immunology- Oct 04-05, 2021- London- UK. Presentation title: “Specificity of CD8+ T-Cell Responses to HIV-1 Vaccines, Lessons for Covid-19“
- Immunology Research Focus Group (IRFG) virtual meeting- NIH-affiliated MENA region, oral presentation entitled: Understanding immune responses to improve vaccine design. March 9, 2021
- BSI Congress 2019, ACC Liverpool, UK, Dec 2-5, 2019. Presentation title: Mapping of HIV-1 CD8 T-cell epitopes in East African recipients of conserved-region T-cell vaccines.
- GCCMID2018, Gulf Congress on Clinical Microbiology and Infectious Diseases, Conrad Hotel Dubai, UAE, Nov 7-10th 2018, Poster presentation entitled “Innovative HIV-1-specific CD8 T-cell epitopes revealed in human recipients of conserved-proteome T-cell vaccine”.
- European Oncology Convention, ExCeL, London, UK, June 5-6th 2018. Attendee and workshops participant. ▪ BSI- Oxford Immunology Symposium, Mathematical Institute, Oxford University, 16-17th April 2018, Attendee and workshop participant.
- Pharma middle east conference, Dubai, UAE, Nov 2nd-4th, 2015, poster presentation entitled: Tumor-specific cytotoxic T lymphocytes; a candidate for adoptive immunotherapy of hematological malignancies.
- CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference, Translating Science into Survival, Sheraton, Times Square Hotel, New York, USA, September 16-19, 2015. Participation and poster presentation entitled: Immortalized HMy2/solid tumor hybridomas induce two different tumor antigen-specific T cell clones in vitro.
- The University of Dammam Annual Scientific Research Update: The Medical and Biomedical research 2015; Conference hall, Dammam, KSA, April 5-7th 2015.
- Third international conference on quality assurance in postsecondary education, Sheraton Dammam Hotel, Dammam, Saudi Arabia, April 27-29th 2013
- Leicester University Postgraduate Research Festival, Leicester, UK, 16th June 2011. ▪ International Conference on “Progress in Vaccination Against Cancer” (PIVAC-10) held in St. Catharine’s College, Cambridge, UK, 27–30th September 2010. Participation and poster presentation
The 7th International Conference of Faculty of Pharmacy- Al-Azhar University, Cairo, Egypt. 22-23 Oct 2022. Poster title: "Perspectives of Healthcare Professionals Regarding Factors Associated with Antimicrobial Resistance (AMR) and Their Consequences, a cross sectional study in multiple Saudi Hospitals."
The 4th European Conference on Vaccines and Immunology- Oct 04-05, 2021- London- UK. Presentation title: “Specificity of CD8+ T-Cell Responses to HIV-1 Vaccines, Lessons for Covid-19“
Immunology Research Focus Group (IRFG) virtual meeting- NIH-affiliated MENA region, oral presentation entitled: Understanding immune responses to improve vaccine design. March 9, 2021
BSI Congress 2019, ACC Liverpool, UK, Dec 2-5, 2019. Presentation title: Mapping of HIV-1 CD8 T-cell epitopes in East African recipients of conserved-region T-cell vaccines.
GCCMID2018, Gulf Congress on Clinical Microbiology and Infectious Diseases, Conrad Hotel Dubai, UAE, Nov 7-10th 2018, Poster presentation entitled “Innovative HIV-1-specific CD8 T-cell epitopes revealed in human recipients of conserved-proteome T-cell vaccine”.
European Oncology Convention, ExCeL, London, UK, June 5-6th 2018. Attendee and workshops participant. ▪ BSI- Oxford Immunology Symposium, Mathematical Institute, Oxford University, 16-17th April 2018, Attendee and workshop participant.
Pharma middle east conference, Dubai, UAE, Nov 2nd-4th, 2015, poster presentation entitled: Tumor-specific cytotoxic T lymphocytes; a candidate for adoptive immunotherapy of hematological malignancies.
CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference, Translating Science into Survival, Sheraton, Times Square Hotel, New York, USA, September 16-19, 2015. Participation and poster presentation entitled: Immortalized HMy2/solid tumor hybridomas induce two different tumor antigen-specific T cell clones in vitro.
The University of Dammam Annual Scientific Research Update: The Medical and Biomedical research 2015; Conference hall, Dammam, KSA, April 5-7th 2015.
Third international conference on quality assurance in postsecondary education, Sheraton Dammam Hotel, Dammam, Saudi Arabia, April 27-29th 2013
Leicester University Postgraduate Research Festival, Leicester, UK, 16th June 2011. ▪ International Conference on “Progress in Vaccination Against Cancer” (PIVAC-10) held in St. Catharine’s College, Cambridge, UK, 27–30th September 2010. Participation and poster presentation
Memberships, Awards and Honors
- Highest Achiever of Faculty Continuing Professional Development (Issued by TLC of AU) as it pertains to Teaching and Learning in the College of Medicine in the academic year 2021-2022
- Medical Laboratory Professional's Association of Ontario (MLPAO), Canada. Member (Jul 2020- present).
- Canadian Society for Medical Laboratory Science (CSMLS). Member (Jul 2020- present)
- The Egyptian MoHP, Licensed Medical Laboratory Specialist (Mar 2020- present)
- Oxford University's Macrophage/ Neutrophil Research club, Member (Oct 2017- present)
- The American Association for Cancer Research (AACR), member (2015- 2016)
- The British Society for Immunology (BSI), member (Jun 2008 - present)
- The Egyptian Pharmacists Syndicate (EPS), active member (2000- present)